Actively Recruiting
Disease Activity Biomarkers in Patients With Systemic Lupus Erythematosus
Led by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Updated on 2022-07-05
250
Participants Needed
1
Research Sites
967 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this research project is to better understand the origin and clinical significance of two lupus-specific "genetic signatures" (IFN signature and plasma cell signature) in patient subgroups with well-defined clinical characteristics. Our aim is to correlate these genetic signatures with cell activation profiles and the production of specific cytokines in different populations from whole blood and in short-term cultures of these circulating cells.
CONDITIONS
Official Title
Disease Activity Biomarkers in Patients With Systemic Lupus Erythematosus
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fulfilment of the EULAR/ACR classification criteria of SLE.
- 18 years of age or above.
- Incident or flare biopsy-proven proliferative or membranous lupus nephritis.
You will not qualify if you...
- Antiphospholipid syndrome nephropathy (APSN).
- Pregnancy at baseline (pregnancy during follow-up will not lead to exclusion).
- Anticipated non-adherence to therapy.
- Medical conditions interfering with outcome evaluations.
- Inability to read and/or sign the informed consent form.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cliniques universitaires Saint-Luc
Brussels, Belgium, 1200
Actively Recruiting
Research Team
F
Frédéric Houssiau, Pr
CONTACT
F
Farah Tamirou, Pr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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