Actively Recruiting

Phase 4
Age: 18Years - 40Years
FEMALE
Healthy Volunteers
NCT05674513

Disparities in Emergency Contraceptive Metabolism Dictate Efficacy

Led by Oregon Health and Science University · Updated on 2024-08-19

140

Participants Needed

1

Research Sites

259 weeks

Total Duration

On this page

Sponsors

O

Oregon Health and Science University

Lead Sponsor

E

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not. The investigators want to learn if genetic differences impact the risk of emergency contraception failure.

CONDITIONS

Official Title

Disparities in Emergency Contraceptive Metabolism Dictate Efficacy

Who Can Participate

Age: 18Years - 40Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Generally healthy women
  • Aged 18 to 40 years
  • Have regular menstrual cycles occurring every 21 to 35 days
  • Experiencing ovulatory cycles confirmed by a progesterone level of 3 ng/mL or greater during the luteal phase of the screening cycle
Not Eligible

You will not qualify if you...

  • Pregnant, seeking pregnancy, or breastfeeding
  • Known allergy to the study medication
  • Recent use of hormonal contraception
  • Irregular menstrual cycles (less than 21 days or more than 35 days)
  • Routine use of nonsteroidal anti-inflammatory drugs
  • Presence of metabolic disorders
  • Smoking
  • Any condition that prevents provision of informed consent
  • Use of drugs within 2 weeks of enrollment that interfere with ulipristal acetate metabolism or are CYP3A4 inducers, inhibitors, or CYP3A drug substrates

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

OHSU

Portland, Oregon, United States, 97239

Actively Recruiting

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Research Team

W

Women's Health Research Unit Department of OB/GYN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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