Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
NCT07220525

Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation

Led by University of California, San Francisco · Updated on 2026-01-23

100

Participants Needed

1

Research Sites

76 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode following a night of disrupted or poor-quality sleep. This prospective, randomized, case-crossover study aims to examine the acute effects of sleep disruption on clinically relevant cardiac ectopy pertinent to AF.

CONDITIONS

Official Title

Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Are age 21 years or older
  • Have a HGNS device implanted for obstructive sleep apnea and followed up at UCSF Health
  • Are willing to abstain from using the upper airway stimulation device for no more than two consecutive days as instructed over the 14-day trial period
  • Able and willing to provide written informed consent
Not Eligible

You will not qualify if you...

  • Currently pregnant or trying to get pregnant
  • Are currently taking class 1 or 3 anti-arrhythmic medications
  • Have a history of permanent AF or expected to have continuous AF throughout the study period
  • Have congenital heart disease
  • Ventricular pacing >40%
  • Are unable to read or sign to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UCSF Medical Center at Parnassus

San Francisco, California, United States, 94143

Actively Recruiting

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Research Team

H

Hannah Oo, BS

CONTACT

B

Bella Peña, BA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation | DecenTrialz