Actively Recruiting
Distance-Based Exercise to Preserve Function and Prevent Disability
Led by Alliance for Clinical Trials in Oncology · Updated on 2026-04-07
104
Participants Needed
17
Research Sites
53 weeks
Total Duration
On this page
Sponsors
A
Alliance for Clinical Trials in Oncology
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial studies whether an exercise program can be successfully delivered to patients receiving treatment for cancer through virtual sessions and allow patients to exercise in their own home. Treatments for cancer can cause side effects such as fatigue and loss of strength. These side effects can make it difficult to work, take care of family, and do other things the patient wants to do. Preliminary research shows that exercise can help prevent some of these side effects, but it can be more difficult to start an exercise program when a patient is receiving cancer treatment. The exercise program in this study is delivered through telehealth (TH) video calls. The TH sessions are delivered by trained staff that supervise resistance exercises. The trained staff also provide guidance to the patient on completing unsupervised aerobic sessions on their own. This may be a successful way to deliver an exercise program and make it easier for cancer patients to exercise in their own home during treatment.
CONDITIONS
Official Title
Distance-Based Exercise to Preserve Function and Prevent Disability
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed cancer diagnosis
- Starting outpatient cytotoxic chemotherapy for curative intent lasting at least 10 weeks
- Enrollment and baseline measures collected by second chemotherapy cycle
- Receiving chemotherapy for solid tumors or hematologic malignancies with curative intent
- Age between 18 and 64 years
- No metastatic cancer
- No severe cardiovascular, respiratory, or musculoskeletal disease or joint problems preventing moderate physical activity
- Not pregnant or breastfeeding
- No current alcohol or substance abuse
- Employed full-time (at least 30 hours per week) at cancer diagnosis
- No engagement in competitive sports or twice weekly resistance training in the past year
- Able to walk for 6 minutes (assistive devices allowed)
- Not participating in other weight loss, physical activity, or dietary intervention trials
- Predicted 6 Minute Walk Test distance of 450 meters or less
- Able to read and understand English
- Not deaf or blind
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 17 locations
1
Kaiser Permanente Dublin
Dublin, California, United States, 94568
Actively Recruiting
2
Kaiser Permanente-Fremont
Fremont, California, United States, 94538
Actively Recruiting
3
Kaiser Permanente Fresno Orchard Plaza
Fresno, California, United States, 93720
Actively Recruiting
4
Kaiser Permanente-Modesto
Modesto, California, United States, 95356
Actively Recruiting
5
Kaiser Permanente-Oakland
Oakland, California, United States, 94611
Actively Recruiting
6
Kaiser Permanente-South Sacramento
Sacramento, California, United States, 95823
Actively Recruiting
7
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, United States, 95119
Actively Recruiting
8
Kaiser San Rafael-Gallinas
San Rafael, California, United States, 94903
Actively Recruiting
9
Kaiser Permanente-Vallejo
Vallejo, California, United States, 94589
Actively Recruiting
10
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
11
Novant Health Cancer Institute - Kernersville
Kernersville, North Carolina, United States, 27284
Actively Recruiting
12
Novant Health Cancer Institute - Mount Airy
Mount Airy, North Carolina, United States, 27030
Actively Recruiting
13
Novant Health Forsyth Medical Center
Winston-Salem, North Carolina, United States, 27103
Actively Recruiting
14
UPMC Hillman Cancer Center at Butler Health System
Butler, Pennsylvania, United States, 16001
Actively Recruiting
15
IRMC Cancer Center
Indiana, Pennsylvania, United States, 15701
Actively Recruiting
16
UPMC Hillman Cancer Center - New Castle
New Castle, Pennsylvania, United States, 16105
Actively Recruiting
17
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania, United States, 16346
Actively Recruiting
Research Team
L
Lilli Johnson
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here