Actively Recruiting
Comparison of Distolingual Infiltration with Conventional Inferior Alveolar Nerve Block Alone for Mandibular Third Molar Extraction
Led by Watim Medical & Dental College · Updated on 2026-01-06
120
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness of adding a distolingual infiltration technique to the conventional inferior alveolar and buccal nerve blocks during mandibular third molar (wisdom tooth) extraction. This randomized controlled trial aims to determine if this additional infiltration can better control pain during the surgery, particularly in the distolingual gingiva, which may not be fully anesthetized with traditional nerve blocks. The study will enroll 120 healthy adult patients aged 18 to 45 years. Participants will be randomly assigned to one of two groups. One group will receive the standard inferior alveolar and buccal nerve block with 2% lignocaine and adrenaline, while the other group will receive the same conventional nerve block plus an additional small dose (0.2 ml) of distolingual infiltration. The study focuses on comparing pain levels during two specific surgical steps: mucoperiosteal flap elevation and bone guttering. During the surgery, pain will be measured using a Visual Analogue Scale from 0 to 10. Patients will be closely monitored on the day of surgery to assess their pain experience. The research team will collect data specifically on pain during flap elevation and bone guttering. This trial is sponsored by Watim Medical & Dental College and is expected to be completed by April 2026.
CONDITIONS
Brief Title
Distolingual Infiltration Verses Conventional Nerve Block in Mandibular Third Molar Extraction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy individuals
- Male and female
- Age 18 to 45 years
- Mandibular third molar impaction of any position
- Mandibular third molar impaction of any class
You will not qualify if you...
- ASA status III and above
- Patients requiring multiple tooth extractions in the same appointment
- Allergy to lignocaine
- Patients for whom adrenaline is contraindicated
- Medically compromised individuals, such as those with poorly controlled diabetes or hypertension
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants receive either conventional inferior alveolar and buccal nerve block or the same with additional distolingual infiltration during mandibular third molar extraction surgery.
1 visit (in-person) on the day of surgery
Duration - Same day as surgery
Participants have pain assessed during mucoperiosteal flap elevation and bone guttering on the day of surgery.
1 visit (in-person) on the day of surgery
Trial Site Locations
Total: 1 location
1
Dr Aimen Zafar
Islamabad, Pakistan
Actively Recruiting
Research Team
D
dr aimen zafar Aimen zafar, bds
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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