Actively Recruiting
Diuretic Effect of Aminophylline and Furosemide in Adult Patients Undergoing Cardiac Surgical Procedures
Led by Cairo University · Updated on 2026-01-21
106
Participants Needed
1
Research Sites
27 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This work aims to investigate the diuretic effect of Aminophylline in comparison to Furosemide in adult patients undergoing cardiac surgical procedures.
CONDITIONS
Official Title
Diuretic Effect of Aminophylline and Furosemide in Adult Patients Undergoing Cardiac Surgical Procedures
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age from 18-65 years.
- Both sexes.
- Adult patients presenting for elective cardiac surgical procedures performed on cardiopulmonary bypass including coronary artery bypass surgery, cardiac valve repair and/or replacement, repair of large septal defects, repair and/or palliation of congenital heart defects, transplantation, and surgery of thoracic aneurysms.
- Body mass index (BMI) between 20 and 40 kg/m2.
You will not qualify if you...
- Sensitivity or contraindication to Aminophylline or Furosemide.
- Stage-5 chronic kidney disease with glomerular filtration rate (GFR) less than 15 mL/min.
- Chronic kidney disease defined by GFR less than 60 mL/min and albumin greater than 30 mg per gram of creatinine with kidney structure or function abnormalities for more than three months.
- Recipients of dialysis before surgery.
- Recipients of solid-organ transplantation before surgery.
- Emergency cardiac surgical procedures (e.g., left main coronary artery bypass graft, stuck valves).
- Patient refusal.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Cairo University
Cairo, Egypt, 12613
Actively Recruiting
Research Team
A
Ahmed M Hassan, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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