Visual contribution to postural stability: Interaction between target fixation or tracking and static or dynamic large-field stimulus.
J Laurens, L Awai, C J Bockisch...
https://pubmed.ncbi.nlm.nih.gov/19775892Actively Recruiting
Led by Dominik Straumann · Updated on 2025-09-19
240
Participants Needed
2
Research Sites
30 weeks
Total Duration
D
Dominik Straumann
Lead Sponsor
U
University Hospital, Zürich
Collaborating Sponsor
This research project studies how balance is affected by special visual stimulation called optokinetic stimulation, which can cause dizziness known as visually induced dizziness (VID). The study focuses on patients with ongoing symptoms after a concussion and those with non-traumatic dizziness, comparing them to healthy participants to better understand the balance and symptom responses. The aim is to improve objective diagnosis of VID and support better treatment and management for affected patients. Participants undergo optokinetic stimulation using either a physical rotating disc or virtual reality goggles that display bright moving dots in specific patterns and directions. Healthy subjects experience a cross-over design, receiving both physical and virtual stimulations in varied sequences, while patients are examined with either physical or virtual stimulation to avoid excessive symptoms. Each stimulation trial lasts about 30 seconds in a controlled dark environment. During the study, researchers record participants' balance responses and document symptoms like dizziness, headache, and nausea at multiple time points during and after stimulation. The main outcome measures include the sensitivity of postural responses to visual stimuli, different postural characteristics, and the severity of visually induced dizziness. The study runs from May 2025 until October 2027, involving randomized participant allocation and single masking to support reliable assessment.
CONDITIONS
Dizziness Due to Visual Stimuli in Patients With Concussion and Other Causes of Dizziness: Examination of Balance Behaviour
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single day
Participants undergo objective balance assessments using physical and/or virtual optokinetic stimulation to evaluate postural responses under different visual stimuli.
1 to 2 visits depending on assigned intervention sequence
Total: 2 locations
1
BrainCare Medical Group
Zurich, Canton of Zurich, Switzerland, 8002
Actively Recruiting
2
University Hospital Zurich, Department of Neurology
Zurich, Canton of Zurich, Switzerland, 8006
Actively Recruiting
D
Dominik Straumann, Prof. Dr. med.
S
Samuel Meyer, MSc
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
DIAGNOSTIC
Number of Arms
4
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
J Laurens, L Awai, C J Bockisch...
https://pubmed.ncbi.nlm.nih.gov/19775892K Agarwal, A M Bronstein, M E Faldon...
https://pubmed.ncbi.nlm.nih.gov/22113702Terry D Fife, Christopher Giza
https://pubmed.ncbi.nlm.nih.gov/24057827Alexandre R Bisdorff, Jeffrey P Staab, David E Newman-Toker
https://pubmed.ncbi.nlm.nih.gov/26231270Anthony P Kontos, Alicia Sufrinko, Natalie Sandel...
https://pubmed.ncbi.nlm.nih.gov/30855306Angelique Van Ombergen, Astrid J Lubeck, Vincent Van Rompaey...
https://pubmed.ncbi.nlm.nih.gov/27128970Marousa Pavlou, Rosalyn A Davies, Adolfo M Bronstein
https://pubmed.ncbi.nlm.nih.gov/17538212Jon S Patricios, Kathryn J Schneider, Jiri Dvorak...
https://pubmed.ncbi.nlm.nih.gov/37316210M Guerraz, L Yardley, P Bertholon...
https://pubmed.ncbi.nlm.nih.gov/11459755Charlotte De Vestel, Willem De Hertogh, Vincent Van Rompaey...
https://pubmed.ncbi.nlm.nih.gov/35685740