Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT06893029

Dizziness Due to Visual Stimuli in Patients With Concussion and Other Causes of Dizziness: Examination of Balance Behaviour

Led by Dominik Straumann · Updated on 2025-09-19

240

Participants Needed

2

Research Sites

128 weeks

Total Duration

On this page

Sponsors

D

Dominik Straumann

Lead Sponsor

U

University Hospital, Zürich

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research project aims to measure how balance is affected by special visual stimulation. Dizziness caused by complex moving visual patterns, known as optokinetic stimulation, is usually called visually induced dizziness (VID). The study includes patients with persistent symptoms after a concussion and those with non-traumatic dizziness. Healthy participants serve as a control group for the comparison of balance and symptom responses. The optokinetic stimulation is done using either a physical rotating disk or a virtual reality (VR) headset. The visual effects are created by bright moving dots. During the stimulation, these patterns move in a specific manner and directions while the subject's balance is recorded. Symptoms such as dizziness, headache, and nausea are also documented. The goal of this project is to improve objective diagnosis of VID. By comparing patients and healthy subjects, the study aim to assess the severity of the disorder. It is also assumed that using different visual stimuli during the balance assessment will offer more sensitive and accurate results. In the long term, this innovative assessment method shall support clinicians to establish the diagnosis of VID, and improve the treatment and management of patients with VID.

CONDITIONS

Official Title

Dizziness Due to Visual Stimuli in Patients With Concussion and Other Causes of Dizziness: Examination of Balance Behaviour

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 60 years
  • Binocular vision
  • Recent concussion or mild traumatic brain injury within 4 weeks to 18 months for concussed patients
  • Diagnosis related to dizziness or visually induced dizziness within 4 weeks to 18 months for non-concussed dizzy patients, including vestibular migraine
  • Signed informed consent form for participation or general consent if retrospective inclusion
Not Eligible

You will not qualify if you...

  • Body mass index greater than 30
  • Acute vestibular syndrome lasting at least 24 hours
  • Severe visual impairment not correctable
  • Balance problems not related to dizziness, such as neurological conditions (e.g., migraine), orthopedic conditions (e.g., lower limb injury), infectious diseases, or other medical causes
  • Dizziness caused by prescribed drugs, substance abuse, or mental disorders
  • Cognitive impairments preventing understanding of study tasks
  • History of traumatic brain injury in the last 12 months
  • History of severe traumatic brain injury with lasting impairments
  • Other confounding conditions like psychiatric disease
  • Frequent episodes of spinning vertigo

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

BrainCare Medical Group

Zurich, Canton of Zurich, Switzerland, 8002

Actively Recruiting

2

University Hospital Zurich, Department of Neurology

Zurich, Canton of Zurich, Switzerland, 8006

Actively Recruiting

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Research Team

D

Dominik Straumann, Prof. Dr. med.

CONTACT

S

Samuel Meyer, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

DIAGNOSTIC

Number of Arms

4

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