Actively Recruiting
DNA Repair Activity in the Skin of Day and Night Shift Workers
Led by Wright State University · Updated on 2025-02-06
48
Participants Needed
1
Research Sites
155 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day shift workers. After the skin biopsies are obtained, they will be brought to the laboratory to be exposed to UVB radiation and to measure UVB responses.
CONDITIONS
Official Title
DNA Repair Activity in the Skin of Day and Night Shift Workers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female
- Fair skin type Fitzpatrick I or II
- Age between 18 and 40 years
- Able to understand study procedures and risks
- Primarily work and stay awake during normal daylight hours (6 am to 6 pm) or night shift hours (6 pm to 6 am) over the past 3 months
- Able to complete a 3-month calendar of work schedule
You will not qualify if you...
- Known photosensitivity
- Currently taking photosensitizing medications
- Diabetes Mellitus
- Use of hormonal agents such as birth control pills
- History of abnormal scarring
- History of skin infections
- History of skin cancers
- History of sleep disorders like sleep apnea or insomnia
- Allergy to lidocaine local anesthetic
- Pregnancy or nursing
- Other serious health issues
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Wright State Physicians
Fairborn, Ohio, United States, 45324
Actively Recruiting
Research Team
M
Manager, Clinical Research Operations
CONTACT
R
Regulatory Specialist
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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