Actively Recruiting

Age: 18Years +
All Genders
NCT04689750

Donor CHIP and Allogeneic HSCT Outcome

Led by The University of Hong Kong · Updated on 2022-10-04

850

Participants Needed

1

Research Sites

312 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Current data on the impact of donor CHIP on long-term recipient outcome remain largely speculative. Data on the impact of donor CHIP including on allograft function, immunologic dysfunction, graft versus host disease (GVHD), disease relapse and survival across various donor populations are scarce. This is a retrospective-prospective cohort study designed to determine the association between donor gene mutations and outcome following allogeneic HSCT.

CONDITIONS

Official Title

Donor CHIP and Allogeneic HSCT Outcome

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult aged 18 year or above
  • Donor and recipient of allo-HSCT
  • Provided signed written informed consent for clinical data and specimen use in prospective or partial prospective/retrospective cases
  • Provided prior signed written informed consent for voluntary use of archived specimens in retrospective cases
Not Eligible

You will not qualify if you...

  • Autologous peripheral blood stem cells or bone marrow stem cell donors for autologous HSCT

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The University of Hong Kong

Hong Kong, Hong Kong

Actively Recruiting

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Research Team

H

Harinder Gill, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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