Actively Recruiting

Age: 18Years +
FEMALE
NCT05599178

Doppler Findings in the Fetal Cerebral Blood Vessels (VA/MCA) Within 24 Hours Before Delivery and Relation With Perinatal Outcome.

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-01

120

Participants Needed

1

Research Sites

157 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

1. Assess differences in flow patterns in the fetal cerebral blood vessels within 24 hours before delivery between fetuses with a normal vs. adverse perinatal outcome. 2. Explore maternal and/or fetal characteristics that might influence technical feasibility of doppler sonography of the fetal cerebral blood vessels in early labor at term. 3. Assess reliability of the technique by measuring intra- and inter-observer variation in a subset of participants.

CONDITIONS

Official Title

Doppler Findings in the Fetal Cerebral Blood Vessels (VA/MCA) Within 24 Hours Before Delivery and Relation With Perinatal Outcome.

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Singleton pregnancy
  • Term gestation between 37 and 42 weeks
  • Fetus in cephalic (head-down) presentation
  • No known fetal chromosomal or severe congenital anomaly
  • Normal fetal growth confirmed by ultrasound between 30 and 37 weeks
  • No pre-existing Doppler or amniotic fluid abnormalities
  • Normal fetal heart rate tracing (CTG) without signs of hypoxia
  • Admission in early spontaneous labor or induction of labor with expected delivery within 24 hours
  • Maternal age 18 years or older
  • Willing to give written informed consent
Not Eligible

You will not qualify if you...

  • Advanced labor with more than 4 cm cervical dilatation at admission
  • Severe chronic maternal medical conditions or poor obstetric history with increased risk of adverse perinatal outcome (such as uncontrolled hypertension, severe pre-eclampsia, uncontrolled diabetes, maternal sepsis, major bleeding, intra-uterine infection, prolonged rupture of membranes over 18 hours)
  • Intra-uterine fetal demise or death
  • Prelabour rupture of membranes with meconium-stained amniotic fluid
  • Patients not meeting all inclusion criteria or refusing to give written informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospitals Leuven, department of obstetrics and gynaecology

Leuven, Belgium, 3000

Actively Recruiting

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Research Team

B

Bram Packet

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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