Actively Recruiting
Dose-Deescalated 3-Fraction Stereotactic Body Radiotherapy For Centrally Located Lung Cancer
Led by Yale University · Updated on 2025-05-14
36
Participants Needed
6
Research Sites
487 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this trial is to test a deescalated 3-fraction stereotactic body radiotherapy (SBRT) regimen to 45 Gray (Gy) in 3 fractions for centrally located thoracic tumors.
CONDITIONS
Official Title
Dose-Deescalated 3-Fraction Stereotactic Body Radiotherapy For Centrally Located Lung Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Lung tumors must be 5 cm or smaller and centrally located near critical chest structures as defined by specific criteria.
- Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 to 2.
- Age greater than 18 years.
- Signed study-specific consent form.
You will not qualify if you...
- Prior radiation therapy near the target lesion with overlapping treatment fields exceeding defined dose limits to critical organs.
- Active systemic, lung, or pericardial infections.
- Interstitial pneumonia or severe symptomatic interstitial lung fibrosis.
- Pregnant or lactating individuals.
- Any medical condition or reason deemed by the investigator to prevent safe participation in the study.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Smilow Cancer Hospital Care Center at Greenwich
Greenwich, Connecticut, United States, 06830
Actively Recruiting
2
Smilow Cancer Hospital Care Center - Guilford
Guilford, Connecticut, United States, 06437
Actively Recruiting
3
Smilow Cancer Hospital - Hamden Care Center
Hamden, Connecticut, United States, 06518
Actively Recruiting
4
Smilow Cancer Hospital
New Haven, Connecticut, United States, 06511
Actively Recruiting
5
Smilow Cancer Hospital Care Center - Trumbull
Trumbull, Connecticut, United States, 06611
Actively Recruiting
6
Smilow Cancer Hospital Care Center - Waterford
Waterford, Connecticut, United States, 06385
Actively Recruiting
Research Team
H
Henry S. Park, MD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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