Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT06378450

Dose-Response Effects of Mindfulness Meditation

Led by University of Melbourne · Updated on 2025-03-30

860

Participants Needed

1

Research Sites

60 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this randomized controlled trial is to test for evidence of dose-response effects in a sample of healthy adults with little to no prior experience with meditation. The main question it aims to answer is whether larger doses of mindfulness meditation yield greater positive changes in wellbeing than smaller doses. Our hypotheses are that (1) larger doses of mindfulness training will yield significantly larger effects, and (2) different doses will be significantly associated with variation in participant engagement, with lower engagement associated with higher doses. Researchers will compare each of three dose conditions, 10-min, 20-min, 30-min, against a minimal dose condition of 3-4 min. Participants will take a 28-day mindfulness meditation course, with guided audio instructions provided daily throughout the intervention period (excluding one rest day per week). They will also be asked to respond to surveys before, during, and after the intervention.

CONDITIONS

Official Title

Dose-Response Effects of Mindfulness Meditation

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Reside in Australia with no plans to relocate or travel overseas during the intervention period
  • Sufficient English comprehension to complete study measures
  • Register for an account and agree to study terms and conditions
  • If experiencing moderate anxiety or depression, agree to continue recommended medical treatment and seek help if symptoms worsen
  • Have no or minimal prior meditation experience (less than 25 hours in the past 6 months and never attended a multi-day mindfulness course)
  • If recruitment is slow, may include participants with up to 100 hours meditation in the past 6 months
Not Eligible

You will not qualify if you...

  • Current or lifetime serious mental illness such as neurodevelopmental, schizophrenia spectrum, bipolar, obsessive-compulsive, trauma-related, dissociative, or personality disorders
  • Severe anxiety or depression symptoms above defined thresholds
  • Severe psychological distress symptoms
  • Scores above thresholds for mania, suicidal ideation, psychosis, repetitive thoughts/behaviors, or dissociation
  • Moderate use of alcohol, tobacco, or drugs
  • Diagnosed neurological conditions like traumatic brain injury, epilepsy, or stroke
  • Serious medical conditions such as cancer, thyroid disorder, or multiple sclerosis
  • Recent bereavement or major loss
  • History of untreated traumatic experiences or adverse childhood events

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Contemplative Studies Centre, The University of Melbourne

Carlton, Victoria, Australia

Actively Recruiting

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Research Team

N

Nicholas T Van Dam, PhD

CONTACT

N

Nicholas I Bowles

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

4

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Dose-Response Effects of Mindfulness Meditation | DecenTrialz