A Study Comparing Two Medications Misoprostol and Oxytocin Versus One Medication Oxytocin Only to Prevent Early Postpartum Bleeding in Women

What this Trial Is About

Researchers are evaluating whether using two medications at the same time, misoprostol and oxytocin, is more effective than using only oxytocin in preventing early postpartum hemorrhage, which is heavy bleeding after childbirth. This bleeding is a leading cause of maternal illness and death worldwide. The study aims to find out if the combination reduces blood loss better and to identify any side effects compared to the standard single medication treatment. Participants will be randomly assigned to one of two groups. One group will receive the standard care of intravenous oxytocin after delivery, while the other group will receive both oxytocin intravenously and misoprostol given under the tongue at the same time. This approach is designed to test the effectiveness and safety of the double medication regimen during the critical period after childbirth. During the study, researchers will measure the amount of blood lost after delivery to compare the two treatment groups. They will also monitor for any serious side effects recorded in medical records. The study is expected to last about one year from the start of participant enrollment, with ongoing observations and data collection throughout that time.

Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum Hemorrhage