Actively Recruiting

Age: 45Years +
FEMALE
NCT02296307

DOvEE - Diagnosing Ovarian & Endometrial Cancer Early

Led by McGill University · Updated on 2024-05-02

13600

Participants Needed

8

Research Sites

730 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study hopes to improve early detection of ovarian and endometrial cancers. It will determine if women with bloating, abdominal distension, abdominal/pelvic pain, increased urinary frequency and/or early satiety, benefit from earlier surgery after screening by CA-125 ovarian cancer biomarker and transvaginal ultrasound.

CONDITIONS

Official Title

DOvEE - Diagnosing Ovarian & Endometrial Cancer Early

Who Can Participate

Age: 45Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Sign an approved informed consent form (ICF).
  • Be 45 years of age or older.
  • Have at least one symptom for 2 weeks to 1 year including: feeling full after eating a few bites, loss of appetite; bowel changes such as diarrhea, constipation, fullness, pain or burning; bloating or abdominal swelling; unexplained weight loss; nausea, vomiting, heartburn, gas, burping, indigestion; increased urinary frequency, urgency, or related symptoms; vaginal discharge, bleeding, spotting, deep pain during intercourse; or discomfort/pain in abdomen, pelvic region, or lower back.
  • Willingness to comply with study protocol.
Not Eligible

You will not qualify if you...

  • Previous bilateral salpingo-oophorectomy (BSO).
  • Previous diagnosis of cancer in ovaries, fallopian tubes, or peritoneum.
  • Current bleeding per rectum not caused by hemorrhoids.
  • Current visible blood in urine (frank haematuria).
  • Symptoms requiring urgent clinical evaluation outside the research protocol.

AI-Screening

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Trial Site Locations

Total: 8 locations

1

West Island Cancer Wellness Centre

Kirkland, Quebec, Canada, H9H0C4

Active, Not Recruiting

2

Axion 50 plus

Laval, Quebec, Canada, H7V2S8

Active, Not Recruiting

3

Clinique Familiale Pas-A-Pas

Montreal, Quebec, Canada, H1H 1J6

Withdrawn

4

Clinique Médicale du Haut-Anjou

Montreal, Quebec, Canada, H1M 3M4

Active, Not Recruiting

5

McGill University Health Centre, Royal Victoria Hospital

Montreal, Quebec, Canada, H4A 3J1

Actively Recruiting

6

Queen Elizabeth Health Centre

Montreal, Quebec, Canada, H4A 3L6

Actively Recruiting

7

Lachine Hospital

Montreal, Quebec, Canada, H8S 3N5

Active, Not Recruiting

8

Clinique du Dr. L. Quintal

Saint-Lambert, Quebec, Canada, J4P 2K7

Active, Not Recruiting

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Research Team

L

Lucy Gilbert, MD,MSc,FRCOG

CONTACT

C

Claudia Martins, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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