Randomized Pilot Study Comparing Safety of Drain vs No Drain Placement After Live Donor Liver Removal Surgery

What this Trial Is About

Researchers are evaluating the safety of using an abdominal drain versus no drain after donor hepatectomy in live liver donors. This pilot study aims to compare these two approaches by measuring the comprehensive complication index CCI at the time of hospital discharge. The CCI score reflects the overall complication burden on patients after surgery, ranging from 0 no complications to 100 death, and is a validated tool for living donor liver transplants. Participants will undergo donor hepatectomy and be randomly assigned to either the drain or no drain group. In the drain group, a 28 Fr abdominal drain will be placed near the cut surface of the liver remnant after confirming hemostasis and biliostasis. In the no drain group, the abdomen will be closed without placing a drain. Both groups will have intraoperative and post-operative parameters compared. During the study, participants will be admitted one day before surgery and monitored until post-operative day 7. Researchers will assess the CCI score on day 7 using an online calculator. Secondary outcomes include infective complications, hospital stay length, paralytic ileus, bile leak, hemorrhage, and pain scores. This thorough monitoring will help evaluate safety differences between the two approaches.

Drain vs No Drain After Live Donor Hepatectomy