Actively Recruiting
Driving Pressure-guided Lung Protective Ventilation
Led by Yong Lin, PhD · Updated on 2025-08-11
43
Participants Needed
1
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving pressure-guided lung protective ventilation can reduce postoperative oxygenation function in patients who have undergone surgical repair of acute type A aortic dissection. The primary outcomes is the incidence of postoperative hypoxemia (a partial pressure of arterial oxygen to inspiratory oxygen fraction ratio less than 300 mm Hg or a peripheral blood oxygen saturation less than 93% at any concentration of inspiratory oxygen) within 7 days after the surgery.
CONDITIONS
Official Title
Driving Pressure-guided Lung Protective Ventilation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to sign informed consent and release medical information forms
- Age between 14 and 70 years old
- Confirmed diagnosis of acute type A aortic dissection by chest computed tomography angiography
- Planned surgical repair for acute type A aortic dissection
You will not qualify if you...
- Age younger than 14 years or older than 70 years
- Sepsis before surgery
- Chronic pulmonary disease including lung infection or asthma requiring long-term medication
- History of lung tumor
- Obstructive sleep apnea hypopnea syndrome requiring long-term noninvasive mechanical ventilation
- Heart failure requiring catecholamines or invasive mechanical ventilation
- Body mass index greater than 30 kg/m2
- Reluctance to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fujian medical university union hospital
Fuzhou, Fujian, China, 350001
Actively Recruiting
Research Team
Y
Yong Lin, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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