Procedural Success and Outcomes of Drug-Coated Coronary Balloons in Various Clinical Scenarios

What this Trial Is About

Researchers are evaluating the use of drug-coated balloons (DCBs) in treating various types of coronary artery disease, including in-stent restenosis, small vessel disease, de novo lesions, chronic total occlusions, and bifurcation lesions. This observational registry aims to gather real-world data on the safety, feasibility, and clinical outcomes of DCB angioplasty across diverse coronary lesion types and patient presentations in Turkey. The study seeks to provide comprehensive evidence beyond traditional uses, addressing both short- and long-term success rates. The study includes patients undergoing percutaneous coronary intervention (PCI) where DCBs are used either alone or with bailout stenting. Detailed information about patient demographics, clinical history, angiographic and procedural details, lesion preparation methods, intravascular imaging, and DCB characteristics will be collected. The registry will analyze procedural success and clinical outcomes such as major adverse cardiovascular events and need for further revascularization, focusing also on the role of lesion preparation and imaging guidance. Participants will be followed for at least 12 months, with data collected on death, revascularization of target lesions and vessels, myocardial infarction, bleeding events, and procedural success. Researchers will monitor clinical progress, collect angiographic and procedural data, and evaluate outcomes to identify factors influencing success or failure of DCB use. This study reflects routine clinical practice and aims to inform future randomized trials comparing DCB strategies with drug-eluting stents.

Drug-Coated Coronary Balloons in Different Clinical Scenarios