Using Drug-Induced Sleep Endoscopy with Propofol Sedation to Evaluate the Airway in Adults with Obstructive Sleep Apnea Considering Surgery

What this Trial Is About

Researchers are studying obstructive sleep apnea OSA in patients considering surgery by using a technique called drug-induced sleep endoscopy DISE to evaluate the upper airway. This method has been shown to have moderate to substantial reliability and has been compared to other evaluation methods like lateral cephalogram X-rays. The study also looks at DISE findings in patients who have not responded to previous sleep apnea surgeries and their association with surgical outcomes. Participants receive sedation through an intravenous propofol infusion to reach a sleep state where they can be awakened by verbal stimuli. This sedation allows doctors to perform the DISE procedure and observe the upper airway during sleep. The study focuses on examining the relationship between DISE results and other physical examinations, sleep studies, and surgical outcomes. During the study, participants undergo DISE with propofol sedation along with other assessments such as polysomnography and physical exams. Researchers measure how DISE correlates with these other evaluations and surgical results both before and after surgery. The study is ongoing with the latest completion date projected for June 2035, and participants are monitored to assess these outcomes throughout the process.

Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea