Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT05424692

Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer

Led by Peking Union Medical College Hospital · Updated on 2024-11-04

200

Participants Needed

1

Research Sites

313 weeks

Total Duration

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AI-Summary

What this Trial Is About

The research objectives is to compare vitro 3D drug sensitivity test results of micro tumor (PTC) with the clinical outcomes of patients, evaluate the consistency between the test results of the technology platform and the clinical prognosis, and explore the decision-making value and guiding significance of this technology in assisting the precise treatment of colorectal cancer. The completion of this study will provide real-world data support for the clinical application of micro tumor (PTC) in vitro 3D drug sensitivity detection technology, and provide more valuable reference basis for realizing the individualization and accuracy of colorectal cancer treatment and improving the clinical benefit rate.

CONDITIONS

Official Title

Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 75 years old, any gender
  • Diagnosed colorectal cancer by histopathology or cytology
  • Require adjuvant therapy after radical surgery without prior neoadjuvant therapy
  • At least one assessable tumor focus present
  • Eastern Cooperative Oncology Group (ECoG) physical condition score of 2 or less
  • Voluntarily agree to participate and sign informed consent
Not Eligible

You will not qualify if you...

  • Presence of metastasis
  • Unable to obtain tumor samples
  • Pregnant or breastfeeding women
  • Poor treatment compliance
  • Severe cardiovascular or cerebrovascular complications preventing adjuvant therapy
  • Having other malignant tumors
  • Serious mental or nervous system diseases
  • Investigator’s decision that the patient should not participate in the study

AI-Screening

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Trial Site Locations

Total: 1 location

1

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 100730

Actively Recruiting

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Research Team

G

Guole Lin

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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