Actively Recruiting
Drug Survival of Target Therapies in Atopic Dermatitis
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-03-18
1167
Participants Needed
1
Research Sites
263 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is an observational study with drug to evaluate the drug survival of approved target therapies in atopic dermatitis. Patients affected by moderate-severe atopic dermatitis who will start therapy with approved target drugs (dupilumab, tralokinumab, upadacitinib, abrocitinib, baricitinib) for AD will be enrolled. Patients already on therapy with these drugs will also be included. During the baseline and follow up visits, clinical and demographic data will be collected, according to ordinary clinical practice. Current or retrospective disease severity scores will also be collected. Among the main: Eczema Area and Severity Index (EASI), Investigator's Global Assessment (IGA), Dermatology Life Quality Index (DLQI), Pruritus Numerical Rating Scale (NRS pruritus), Sleep Numerical Rating Scale (NRS sleep), Patient Oriented Eczema Measure (POEM).
CONDITIONS
Official Title
Drug Survival of Target Therapies in Atopic Dermatitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosed with moderate-to-severe atopic dermatitis (EASI >24)
- Currently undergoing or have undergone systemic therapy with a biological drug or small molecules
- For retrospective data, at least one follow-up visit after treatment start with clinical and demographic data collected at baseline and follow-up
- Signed informed consent for the study and data processing for research
You will not qualify if you...
- Under 18 years of age
- Have undergone systemic therapy with biological drugs or small molecules without available treatment start date or missing clinical-demographic data at baseline and follow-up
- No informed consent for the study and data processing for research purposes
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
fondazione policlinico universitario agostino gemelli IRCCS
Rome, Italy, 00168
Actively Recruiting
Research Team
K
ketty peris, Prof
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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