Actively Recruiting
DSLT for Reducing Medication in Glaucoma
Led by The Eye Institute of West Florida · Updated on 2026-04-20
60
Participants Needed
1
Research Sites
50 weeks
Total Duration
On this page
Sponsors
T
The Eye Institute of West Florida
Lead Sponsor
S
Sengi
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a prospective, single arm, open label study conducted at a single site to evaluate the efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in reducing medication burden in patients with medically controlled ocular hypertension or primary open angle glaucoma. The study will assess the primary endpoint of reduction in medication count at 6 months compared to baseline. Secondary endpoints include IOP reduction compared to baseline (both percentage and absolute), complete success rate (no increase in IOP without medications), proportion of eyes needing medication at 6 months, and any secondary surgical interventions at 6 months post-DSLT. Participants will undergo DSLT with 120 shots, 400 µm spot size, and 1.8mJ fixed energy delivered at the limbus over 2.4 seconds. Follow-up visits will occur at 1 month, 3 months, and 6 months post-procedure, with IOP measured using a calibrated Goldmann tonometer.
CONDITIONS
Official Title
DSLT for Reducing Medication in Glaucoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients scheduled to undergo DSLT treatment in one or both eyes
- Diagnosis of ocular hypertension or primary open angle glaucoma
- Medically controlled on 1-3 topical ocular hypotensive agents with IOP 6421 mmHg
You will not qualify if you...
- Prior glaucoma surgeries or interventions such as trabeculectomy, laser trabeculoplasty, MIGS, or tube shunt
- Cataract surgery within the prior 2 years
- Secondary forms of glaucoma including angle-closure, neovascular, or glaucoma from trauma or systemic diseases
- Other significant eye conditions like advanced cataracts or retinal diseases that could affect IOP or visual function assessment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Eye Institute of West Florida
Largo, Florida, United States, 33770
Actively Recruiting
Research Team
R
Renee Bondurant
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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