Actively Recruiting
dTDI During a SBT to Predict Extubation Failure in Preterm Infants
Led by Wang Jianhui · Updated on 2024-07-16
100
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Weaning from mechanical ventilation is a critical issue and the diaphragmatic disfunction has been demonstrated to play an important role in extubation failure. the aim of present investigation is to evaluate diaphragmatic excursion velocity during in patients undergoing spontaneous breathing trial through tissue Doppler analysis in both inspiration and expiration.
CONDITIONS
Official Title
dTDI During a SBT to Predict Extubation Failure in Preterm Infants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Premature infants with gestational age less than 32 weeks and on invasive mechanical ventilation for at least 48 hours
- Meet all indications for extubation: spontaneous cough or vomiting and sputum aspiration
- Ventilator settings in the last 24 hours: MAP less than 8 cmH2O, respiratory rate less than 30 breaths per minute, FiO2 less than 30%
- Arterial blood gas results: pH greater than 7.25, PaCO2 less than 60 mmHg, base excess less than 8 mmol/L, oxygen saturation over 90%
- Successful completion of a spontaneous breathing trial
- Parents or legal guardians have signed informed consent
You will not qualify if you...
- Accidental extubation
- Chest CT or bronchoscopy indicating congenital airway dysplasia
- Complex congenital heart disease
- Congenital metabolic or neuromuscular diseases
- Severe brain injury
- Surgical mechanical ventilation
- Decision to give up before extubation
- Pneumothorax or pleural effusion
- No consent signed
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Children's hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China, 400014
Actively Recruiting
Research Team
J
Jianhui Wang, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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