Comparing Dual-energy CT and MRI for Assessing Oral and Oropharyngeal Squamous Cell Carcinomas to Improve Diagnosis and Treatment Speed

What this Trial Is About

Researchers are investigating the use of 40keV dual-energy CT scans compared to MRI for assessing squamous cell carcinomas of the oral cavity and oropharynx. The study aims to determine if the dual-energy CT can provide a diagnosis that is not inferior to MRI, potentially speeding up pre-treatment assessments and reducing delays in starting treatment. This evaluation is important because current protocols require both CT and MRI scans, which can slow down the treatment process and limit MRI availability. Participants will undergo both contrast-enhanced cervicofacial MRI and contrast-enhanced cervicofacial dual-energy CT scans using the BOLT maneuver. The study will compare the agreement between these imaging methods in determining the T stage of the tumor according to the TNM classification. This observational study does not involve additional treatments but focuses on comparing diagnostic imaging techniques. During the study, participants will receive clinical examinations including nasofibroscopy by specialized ENT surgeons, as well as the required imaging scans. Researchers will monitor and measure the overall agreement between the CT and MRI results for tumor staging over a period of up to 12 months. The study intends to improve diagnostic efficiency and reduce patient delays without compromising assessment quality.

Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx