Dual-port Trans-subclavian Thyroid Endoscopic Surgery An Evaluation of a New Approach Compared to Conventional Open Thyroidectomy for Thyroid Tumors

What this Trial Is About

Researchers are investigating a new surgical method called Dual-port Trans-subclavian Thyroid Endoscopic Surgery (DTS) for patients with thyroid tumors. This study compares DTS, a less invasive endoscopic technique, with the traditional open thyroidectomy (COT) to explore its effectiveness and safety. The study is open-label, non-randomized, and conducted at a single center, aiming to gather real-world evidence on this novel approach. Thyroid cancer and benign thyroid tumors are the conditions being studied, with an emphasis on improving incision appearance and reducing surgical trauma. The study involves two groups of 150 patients each: one group receives the DTS technique, which uses two small 1 cm puncture holes to reduce surgical trauma and postoperative pain by creating the surgical cavity directly in the neck area. The other group undergoes the traditional open thyroid surgery with collar incisions. DTS offers better visual exposure for lymph node clearance and aims to shorten hospital stays. Both groups will have their laboratory and medical data collected at specified follow-up points, with detailed recording of any adverse events. Participants will be monitored for surgical complications from the time they are assigned to a group until the first relapse of disease progression or death, with follow-up lasting up to 100 months. Secondary measures include immune and hormone levels before and after surgery, pain scores, surgery duration, hospital stay length, treatment costs, drainage volume, and wound satisfaction assessed at three months. Safety assessments include adverse events, vital signs, and pathology exams to ensure thorough evaluation of both techniques.

Dual-port Trans-subclavian Thyroid Endoscopic Surgery