Actively Recruiting

Age: 18Years +
All Genders
NCT06866444

Duloxetine Metabolism and Fibromyalgia

Led by University of Utah · Updated on 2025-08-21

100

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

People with fibromyalgia report generalized body pain ("pain all over"), increased sensitivity to painful stimulation, chronic tiredness or low energy, sleep problems, and other physical and functional problems. The exact cause of the disorder is poorly understood, and treatment can be difficult. The degree to which duloxetine is helpful for people with fibromyalgia varies greatly. For some people, it is very helpful for managing fibromyalgia symptoms. For others, people may not notice any benefit. Yet for some, it is a little helpful and the effect is noticeable only when people forget to take the medicine. The purpose of this study is to collect data to better understand the relationship among gene types that control those enzymes, blood concentrations of duloxetine, and how it helps the symptoms.

CONDITIONS

Official Title

Duloxetine Metabolism and Fibromyalgia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults 18 years or older
  • Diagnosed with fibromyalgia
  • Taking duloxetine 60 mg daily for at least 8 weeks
Not Eligible

You will not qualify if you...

  • Pregnant patients
  • History of kidney or liver dysfunction or history of renal dialysis
  • Require an interpreter to communicate
  • Progressive illnesses other than fibromyalgia with chronic pain and fatigue (e.g., cancer receiving antineoplastic treatment, Parkinson's disease, Multiple Sclerosis)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Pain Management Center and Pain Research Center at the University of Utah

Salt Lake City, Utah, United States, 84132

Actively Recruiting

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Research Team

J

Jake Steenblick, DNP

CONTACT

N

Natalie R Bennion, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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