Actively Recruiting
Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis
Led by Montefiore Medical Center · Updated on 2026-01-22
60
Participants Needed
1
Research Sites
223 weeks
Total Duration
On this page
Sponsors
M
Montefiore Medical Center
Lead Sponsor
R
Regeneron Pharmaceuticals
Collaborating Sponsor
AI-Summary
What this Trial Is About
The central hypothesis of this study is that the addition of dupilumab treatment onto standard-of-care intranasal corticosteroids will improve patient-reported measures of disease activity and sense of smell in a cohort of mostly ethnical and racial minority patients with CRSwNP
CONDITIONS
Official Title
Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with physician-diagnosed chronic rhinosinusitis with nasal polyps (CRSwNP), with or without asthma, meeting FDA-approved criteria for dupilumab use
- Patients aged 18 years and older
- Willing to provide consent to participate in the study
- Have insurance coverage for dupilumab or access through the Dupixent MyWay Program
You will not qualify if you...
- Age under 18 years
- Suspected or diagnosed allergic fungal rhinosinusitis
- Suspected or diagnosed cystic fibrosis
- Dupilumab coverage denied by insurance or Dupixent MyWay Program
- Required a steroid taper in the last 30 days (except those on chronic steroids of 20 mg prednisone daily or less)
- Use of other biologic medications in the past 3 months
- Diagnosis of eosinophilic granulomatosis with polyangiitis (EGPA)/Churg-Strauss Syndrome
- Pregnancy
- Presence of inverted papilloma growth
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Montefiore Medical Center
The Bronx, New York, United States, 10461
Actively Recruiting
Research Team
G
Golda Hudes, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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