Actively Recruiting
Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory Clinic
Led by Akron Children's Hospital · Updated on 2025-09-19
46
Participants Needed
1
Research Sites
110 weeks
Total Duration
On this page
Sponsors
A
Akron Children's Hospital
Lead Sponsor
R
Regeneron Pharmaceuticals
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to test the efficacy of Dupixent in improving post-burn itching symptoms versus the current standard of care.
CONDITIONS
Official Title
Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory Clinic
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 60 years
- Have post-burn hypertrophic scars from acute burn injury requiring grafting or autografting
- Experience ongoing itching due to inadequate relief from standard medical care after at least four weeks
- At least four weeks have passed since their last grafting surgery
- Able to speak English sufficiently to participate in the study
You will not qualify if you...
- Currently using Dupixent for any other diagnosis
- Known allergy to Dupixent
- Pregnant or lactating women
- Treated for itching with laser therapy
- Currently receiving adequate relief from standard medical care with antihistamines or neuroleptic medications
- Taking steroids
- Have developmental delays or unable to complete study measures
- Prisoners or persons unable to give their own consent or who are not their own guardian
- Have conjunctivitis or other dermatological conditions besides burns
- Have any type of cancer
- Require dialysis or have chronic Stage 3 or higher kidney disease
- Have biliary, gall bladder, renal, or hepatic disorders deemed inappropriate for study
- Have other dermatological conditions that could confound results
- Have been treated with laser therapy for itching
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Akron Children's Hospital
Akron, Ohio, United States, 44308
Actively Recruiting
Research Team
A
ANJAY KHANDELWAL, MD
CONTACT
J
Jessica Kracker, BSN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here