Actively Recruiting
DUTCH Weight Control in Atrial Fibrillation Study
Led by Rijnstate Hospital · Updated on 2024-09-19
280
Participants Needed
1
Research Sites
144 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Quantify the effect of an innovative weight loss management on rhythm control.
CONDITIONS
Official Title
DUTCH Weight Control in Atrial Fibrillation Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Symptomatic, first detected persistent atrial fibrillation within 6 months before enrollment
- Age 18 years or older
- Obesity defined as BMI 63 30 kg/m2, or BMI 63 27 kg/m2 with at least one weight-related comorbidity (treated or untreated, such as hypertension, dyslipidaemia, obstructive sleep apnea, cardiovascular disease)
- Scheduled for electrical cardioversion
- Provided written informed consent
You will not qualify if you...
- Permanent atrial fibrillation
- Secondary atrial fibrillation due to thyrotoxicosis, infection, or recent cardiothoracic surgery
- Current or previous treatment with amiodarone
- HbA1c 63 48 mmol/L within 3 months before randomization
- History of diabetes mellitus type 1 or 2
- Prior bariatric surgery
- Use of other anti-obesity medication within 3 months before enrollment
- Contraindication for or prior use of a GLP1-receptor agonist
- History of chronic or acute pancreatitis within 6 months
- Acute coronary syndrome within 6 months
- Severe (grade III) valvular disease
- eGFR less than 30 mL/min/1.73m2
- Heart failure NYHA class III-IV
- Participation in another investigational drug or device study within past 30 days (registry enrollment allowed)
- Any condition or therapy making the participant unsuitable or with life expectancy less than 12 months
- Female who is pregnant, breastfeeding, intends to become pregnant, or is of child-bearing potential without using highly effective contraception
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Rijnstate Hospital
Arnhem, Gelderland, Netherlands
Actively Recruiting
Research Team
L
Leonard Voorhout, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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