Actively Recruiting

Phase 2
Age: 18Years +
All Genders
Healthy Volunteers
NCT06296849

Dyadic Financial Incentive Treatments for Dual Smoker Couples

Led by University of Oklahoma · Updated on 2026-04-29

900

Participants Needed

2

Research Sites

223 weeks

Total Duration

On this page

Sponsors

U

University of Oklahoma

Lead Sponsor

M

McMaster University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Smokers partnered with other smokers (i.e., dual-smoker couples) represent \~2/3 of all smokers. Dual-smoker couples (DSCs) are less likely to try to quit smoking and more likely to relapse during a quit attempt, reducing overall smoking cessation rates and representing a high-risk clinical population. Despite their high prevalence and risk for persistent smoking, however, there are limited data on smoking cessation interventions among DSCs. Building on previous research that suggests a) financial incentive treatments (FITs) are effective at increasing quit rates and b) dyadic adaptations of FITs are feasible for implementation in DSCs, the proposed study will systematically two versions of FITs to enhance smoking cessation among DSCs. In addition to determining the efficacy of these dyadic FITs for smoking abstinence in DSCs, the investigators will consider the cost and cost effectiveness of each adaptation as well as mechanisms of change to inform future implementation research. The investigators will additionally consider secondary outcomes including abstinence during treatment and long-term abstinence maintenance after end of treatment. The investigators will address these questions in a three-group randomized controlled trial (RCT). In all conditions, individuals who have smoking partners (i.e., targets) will receive usual care (combination fast and slow acting Nicotine Replacement Therapy + quitting resources). In two conditions, participants will receive incentives for abstinence at three time points (1, 3, and 6 months post-baseline). In the SFIT condition, only the target in a couple will be offered incentives; in the DFIT condition, both target and partner will be offered incentives. Primary efficacy outcome is % point-prevalence abstinence at 6 months post-baseline among targets. Secondary outcomes are point-prevalence abstinence at 1 and 3 months during the treatment and 6 months post-treatment (12-months post-baseline), as well as partner outcomes. The investigators will evaluate possible mechanisms of change including partner support and individual and partner motivation to quit as well as evaluate the cost and relative cost of each abstainer within and across condition. These data on the efficacy, mechanisms, and costs of FITs for DSCs will inform population level implementation and promote successful quitting in this treatment refractory population.

CONDITIONS

Official Title

Dyadic Financial Incentive Treatments for Dual Smoker Couples

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Smoking 5 or more cigarettes per day
  • Married to or living with a daily smoker who smokes 5 or more cigarettes per day and is at least 18 years old
  • In a romantic relationship lasting at least six months
Not Eligible

You will not qualify if you...

  • Reading and writing ability below 8th grade level in English
  • Hospitalization within the past six months
  • Risk of psychosis
  • Regular use of e-cigarettes 4 or more days per week
  • Contraindications for nicotine replacement therapy, such as pregnancy or heart disease
  • Marijuana use
  • Both members of the couple must meet inclusion and exclusion criteria for the target to enroll

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

University of Georgia

Athens, Georgia, United States, 30602

Completed

2

University of Oklahoma Health Campus

Tulsa, Oklahoma, United States, 74135

Actively Recruiting

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Research Team

M

Michelle R vanDellen, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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