Impact of Dynamic Compliance-Guided Ventilation on Postoperative Pulmonary Function in Lumbar Stabilization Surgery: A Prospective Study

What this Trial Is About

Researchers are investigating a ventilation method called dynamic compliance-guided ventilation during lumbar stabilization surgery to see if it improves postoperative lung function compared to standard ventilation. This study focuses on patients undergoing surgery in the prone position and aims to reduce postoperative pulmonary complications by adjusting ventilator settings based on real-time lung compliance. The primary measure is a modified lung ultrasound score evaluating lung aeration loss, with additional assessments of respiratory and hemodynamic parameters during and after surgery. The study randomly assigns patients to two groups: one receives ventilation adjusted according to dynamic compliance monitoring, where positive end expiratory pressure (PEEP) is carefully titrated to achieve the best lung compliance; the other group receives conventional ventilation settings without dynamic compliance adjustments. Both groups are ventilated in volume-controlled mode with specific tidal volumes and respiratory rates, and all patients undergo recruitment maneuvers to optimize lung function after intubation and positioning. Participants will be monitored before, during, and after surgery with lung ultrasounds at baseline, 1 hour, and 24 hours postoperatively to assess lung condition. Additional monitoring includes intraoperative respiratory pressures, heart rate, blood pressure, oxygen levels, and length of hospital stay. The study follows patients postoperatively for up to 7 days to track pulmonary complications and measures various respiratory mechanics during surgery to evaluate differences between ventilation methods.

Dynamic Compliance-Guided Ventilation in Lumbar Surgery