Actively Recruiting

Age: 18Years +
FEMALE
NCT06420427

Dynamic Monitoring of ctDNA and HPV DNA in Plasma for the Early Prediction of Recurrence After Cervical Cancer Surgery

Led by The Third Affiliated Hospital of Guangzhou Medical University · Updated on 2024-05-20

150

Participants Needed

1

Research Sites

160 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Assess the sensitivity, specificity, positive predictive value, and negative predictive value of dynamic monitoring of circulating tumor DNA (ctDNA) combined with circulating HPV DNA (cfHPV DNA) for early prediction of recurrence in cervical cancer post-surgery or post-treatment, and compare its advantages and disadvantages with existing diagnostic methods.

CONDITIONS

Official Title

Dynamic Monitoring of ctDNA and HPV DNA in Plasma for the Early Prediction of Recurrence After Cervical Cancer Surgery

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with newly diagnosed HPV-positive cervical malignancy at stages I-IV who have not undergone surgery, radiation therapy, or chemotherapy.
  • Patients must be older than 18 years of age.
  • Cervical cancer patients who are eligible for surgery and/or chemoradiotherapy.
  • Estimated life expectancy of more than three months.
  • Understands the study protocol and voluntarily participates in the research by signing the informed consent form.
  • Able to provide specimens and corresponding clinical information at each time point.
Not Eligible

You will not qualify if you...

  • Patients who are participating in other clinical trials.
  • Pregnant or breastfeeding women.
  • Patients with severe mental illness.
  • Patients who voluntarily withdraw.
  • Patients unable to complete the study protocol.

AI-Screening

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Trial Site Locations

Total: 1 location

1

The Third Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China, 510150

Actively Recruiting

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Research Team

X

Xiujie Sheng, Prof

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Dynamic Monitoring of ctDNA and HPV DNA in Plasma for the Early Prediction of Recurrence After Cervical Cancer Surgery | DecenTrialz