Actively Recruiting
Dynamical Electrophysiology and Neuropathology in Lewy's Bodies Disease
Led by University Hospital, Strasbourg, France · Updated on 2026-01-13
40
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Lewy body disease (LBD) is a neurodegenerative disorder that causes cognitive and behavioral problems. However, it is difficult to diagnose, and its pathophysiology is still not fully understood. The usual diagnostic criteria for LBD have excellent specificity but poor sensitivity. In particular, we lack paraclinical tests that can make a significant contribution. LBD patients may exhibit abnormalities in brain activity dynamics, which can be detected by EEG and may be linked to neuronal dysfunctions specific to the disease. The objective of this study is twofold: first, to assess the validity of this observation, that is, to confirm that the observed phenomenon is indeed linked to the pathophysiology of LBD, and second, to clarify the nature of these abnormalities by exploring the brain dynamics of LBD patients in greater detail.
CONDITIONS
Official Title
Dynamical Electrophysiology and Neuropathology in Lewy's Bodies Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult subjects (≥18 years old)
- Participants in the Alpha-Lewy-MA cohort who underwent RT-QuIC analysis
- Subjects who had a standard EEG examination at HUS between January 1, 2012, and January 1, 2020
You will not qualify if you...
- Subjects who expressed opposition to participating in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Service de psychiatrie de la personne âgée - CHU de Strasbourg - France
Strasbourg, France, 67091
Actively Recruiting
Research Team
L
Ludovic DORMEGNY-JEANJEAN, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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