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Actively Recruiting

Age: 18Years +
All Genders
ID06776263

Study of Breathing Problems in Adults With Post COVID-19 Condition

Led by Karolinska Institutet · Updated on 2025-02-14

200

Participants Needed

2

Research Sites

25 weeks

Total Duration

On this page

Sponsors

K

Karolinska Institutet

Lead Sponsor

K

Karolinska University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating dysfunctional breathing in patients with post COVID-19 condition to understand what signs, symptoms, and assessments can describe and explain this issue. The study aims to identify measurements that can detect dysfunctional breathing and to evaluate methods for measuring it regarding validity, reliability, and sensitivity. The research is part of a larger project called ReCOV, which looks at the long-term effects of COVID-19 on patients, their families, and healthcare staff. This observational study has a cross-sectional design and will recruit about 200 patients from the ReCOV cohort and primary care. Participants will be adults over 18 years old who report persistent respiratory problems or suspected dysfunctional breathing patterns. Evaluations include physical and psychological function assessments, questionnaires, and various measurements such as breathing pattern analysis with a Respiratory Movement Measuring Instrument, muscle strength tests, chest mobility, walking endurance, spirometry, diaphragmatic ultrasound, and carbon dioxide levels during exercise. Participants will undergo a one-time assessment using multiple tools to measure breathing patterns, physical activity, symptoms, and health-related quality of life. Questionnaires will evaluate breathing dysfunction, respiratory symptoms, anxiety, depression, and overall health status. The study will also collect data on diaphragm thickness and movement. The primary outcomes focus on breathing pattern and quality of life, with secondary outcomes covering muscle strength, chest mobility, endurance, and other respiratory functions. The study helps to better understand breathing difficulties after COVID-19 and to develop tailored interventions for rehabilitation.

CONDITIONS

Brief Title

Dysfunctional Breathing in Post COVID-19 Condition.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who report persistent respiratory problems
  • Patients with a score of 2 or higher on the mMRC scale
  • Patients with a score of 23 or over on the Nijmegen scale
  • Patients aged 18 years or older
  • Patients able to perform physical and breathing measurements
Not Eligible

You will not qualify if you...

  • Patients unable to perform measurements due to cognitive or physical impairments
  • Patients currently undergoing breathing exercise interventions

Research Team

M

Malin Nygren-Bonnier, Associate professor, PhD

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