Actively Recruiting
e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most
Led by Johns Hopkins University · Updated on 2026-05-04
100
Participants Needed
1
Research Sites
32 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The overarching goal of this study is to pilot an intervention in which older adults with mild cognitive impairment and dementia and the older adult's care partners are identified in primary care and provided with educational materials through the patient portal to engage the participant in deprescribing. The multicomponent intervention, e-Align, includes delivery of educational information through the patient portal, and a pharmacist-led intervention to align medications with patient and care partner goals and reduce use of central nervous system (CNS) potentially inappropriate medicines (PIM). This work will establish the preliminary data, methods, and partnerships to undertake a multisite embedded pragmatic clinical trial. The resulting triadic-based behavioral intervention will promote patient and care partner engagement, and foster care that aligns with patients' values, and promote improved health and well-being outcomes for people with cognitive impairment and the patient's care partners through deprescribing.
CONDITIONS
Official Title
e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 65 years or older
- Diagnosis of mild cognitive impairment or dementia based on ICD-10 codes
- At least one active central nervous system potentially inappropriate medication
- Active users of the patient portal
- Care partners over 21 years old who regularly assist patients with medication management
You will not qualify if you...
- Individuals living in long term care facilities
- Patients enrolled in hospice care
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Johns Hopkins Community Physicians
Baltimore, Maryland, United States, 21209
Actively Recruiting
Research Team
A
Ariel Green, MD, MPH, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
1
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