Actively Recruiting
E-cigarette Cessation in Adults Who Co-use Cannabis
Led by Medical University of South Carolina · Updated on 2025-07-07
105
Participants Needed
3
Research Sites
79 weeks
Total Duration
On this page
Sponsors
M
Medical University of South Carolina
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to better understand tobacco outcomes using a commonly prescribed stop smoking medication (varenicline) and financial incentives for adults who also use cannabis. Varenicline is not FDA approved for e-cigarette cessation, but is FDA approved for cigarette cessation. Investigators are also interested in how cannabis/marijuana and tobacco interact during a tobacco quit attempt. All participants will receive e-cigarette cessation treatment for 12 weeks. To qualify, participants must be between the ages of 18-40 and use both e-cigarettes and cannabis. Participants do not need to be interested in quitting cannabis to qualify. This study is being conducted at three sites: the Medical University of South Carolina in Charleston, SC, Behavioral Health Services in Pickens, SC, and MUSC Lancaster in Lancaster, SC.
CONDITIONS
Official Title
E-cigarette Cessation in Adults Who Co-use Cannabis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between the ages of 18 and 40 years old
- Use e-cigarettes daily or near daily in the past month
- Must submit a positive instant-read urine cotinine test at screening (≥ 200 ng/ml)
- Be interested in quitting use of e-cigarettes
- Must be willing to take varenicline for the standard 12-week course of treatment
- Self-reported use of cannabis on at least 10 out of the past 30 days or must submit a positive qualitative urinary cannabinoid test at screening (> 50 ng/ml)
You will not qualify if you...
- Any serious or unstable medical/psychiatric disorder (including severe substance use disorders, other than cannabis or tobacco use disorders) in the past three months that may interfere with study performance
- Use of cigarettes on 10+ days in the past 30
- Currently pregnant or breastfeeding
- Current use of medications with smoking cessation efficacy
- Use of any medications that would interfere with varenicline
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
MUSC Charleston
Charleston, South Carolina, United States, 29425
Actively Recruiting
2
MUSC Lancaster
Lancaster, South Carolina, United States, 29720
Actively Recruiting
3
Behavioral Health Services of Pickens County
Pickens, South Carolina, United States, 29671
Actively Recruiting
Research Team
E
Elizabeth Chapman, MA, LPC, LAC, AADC
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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