Actively Recruiting
Earlier Diagnosis and Better Treatment Mission Related to the Cohort Programme
Led by Luxembourg Institute of Health · Updated on 2025-08-06
1800
Participants Needed
2
Research Sites
575 weeks
Total Duration
On this page
Sponsors
L
Luxembourg Institute of Health
Lead Sponsor
U
University of Luxembourg
Collaborating Sponsor
AI-Summary
What this Trial Is About
The Luxembourg Parkinson's Study is an ongoing longitudinal nationwide monocentric observational study. It collects extensive clinical, molecular, genetic, and digital device-based longitudinal data, as well as foreseen post-mortem diagnostic validation (Hipp et al., 2018). The cohort consists of more than 1,600 participants from Luxembourg and the Greater Region, comprising patients with typical PD or atypical parkinsonism - irrespective of disease stage, age, cognitive status, comorbidities, or linguistic background - followed-up annually and age- and sex-matched healthy control subjects followed-up every 4 years. To provide a large, longitudinally followed, and deeply phenotyped set of patients and controls for clinical and fundamental research on PD, the investigators have implemented an open-source digital platform that has been partly harmonized with other international PD cohort studies. This effort is flanked by comprehensive biosampling efforts assuring high quality and sustained availability of body liquids and tissue biopsies (including blood, urine, stool, saliva, hair, skin biopsy and cerebrospinal fluid). All data and samples are stored, curated, and integrated into state-of-the-art data and biobank facilities.
CONDITIONS
Official Title
Earlier Diagnosis and Better Treatment Mission Related to the Cohort Programme
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have Parkinson's disease (typical or atypical parkinsonism) or another neurodegenerative disease
- Are at least 18 years old at the time of inclusion
- Have full capacity to provide consent, or have agreement from a legal guardian/authorized representative
- Are of any gender
You will not qualify if you...
- Refuse to sign the informed consent
- Have limited consent capacity without a legal guardian/authorized representative or lack their agreement
- Have active cancer
- Are pregnant
- Are younger than 18 years old
- Refuse to comply with mandatory sample collection
- Have blood clotting problems that prevent invasive procedures like lumbar puncture or skin biopsy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Centre Hospitalier de Luxembourg (CHL), "Parkinson's Research Clinic"
Luxembourg, Luxembourg, 1210
Actively Recruiting
2
Clinical and Epidemiological Investigation Center (CIEC)
Luxembourg, Luxembourg, 1445
Actively Recruiting
Research Team
R
Rejko KRÜGER, Dr
CONTACT
P
Parkinson clinic
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here