Actively Recruiting
Early Antenatal Support for Iron Deficiency Anemia
Led by Thomas Jefferson University · Updated on 2025-12-02
80
Participants Needed
1
Research Sites
274 weeks
Total Duration
On this page
Sponsors
T
Thomas Jefferson University
Lead Sponsor
A
Auerbach Hematology and Oncology
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a randomized, controlled multi-site trial of iron therapy in pregnancy. The purpose of this research is to see if second trimester initiation of intravenous (IV) iron therapy is better than oral iron therapy for treatment of anemia in pregnancy by improving blood count, quality of life and reducing side effects.
CONDITIONS
Official Title
Early Antenatal Support for Iron Deficiency Anemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant with a single baby (singleton gestation)
- Gestational age less than 24 weeks
- Baseline hemoglobin between 9.0 and less than 11.0 with evidence of iron deficiency anemia
- Iron deficiency anemia diagnosed by hemoglobin less than 11.0
- Ferritin less than 30 and/or total iron saturation less than 20
You will not qualify if you...
- Sickle cell disease (sickle cell trait allowed)
- Acute anemia needing transfusion or intravenous iron therapy
- Major congenital or chromosomal anomalies
- Previous intravenous iron use during this pregnancy
- Severe heart, kidney, or liver disease
- Autoimmune diseases such as systemic lupus erythematosus
- Allergy or contraindication to either study drug
- History of medication allergy, reaction to IV infusion, or reaction to ferumoxytol or other intravenous iron products
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
Research Team
R
Rupsa C Boelig, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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