Actively Recruiting
Early Beta Blocker Administration in STEMI Patients With SCAI B Status
Led by Tel-Aviv Sourasky Medical Center · Updated on 2025-05-28
200
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is looking at how a medication called beta-blockers (metoprolol) affects patients with a heart attack (STEMI) who are in the cardiac intensive care unit. When patients are admitted to the unit, they will be randomly placed in one of two groups. One group will get the metoprolol medication, and the other will receive a placebo (a harmless pill that looks like the real medication). All other treatments will be the same for both groups. During the study, which is 72 hours long, patients will be monitored for blood pressure, heart rate, and lactate levels alterations. The main goal is to see if the medication helps improve patients condition or prevent it from getting worse. patients safety is a top priority, and if needed, the doctors can stop the study at any time if there are concerns.
CONDITIONS
Official Title
Early Beta Blocker Administration in STEMI Patients With SCAI B Status
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of ST-segment elevation myocardial infarction (STEMI) confirmed by ECG, clinical signs, and coronary catheterization
- Classified as SCAI B status upon admission, showing tachycardia and/or hypotension without signs of hypoperfusion
- Age 18 years or older
- Mentally competent to provide informed consent and comply with study procedures
You will not qualify if you...
- Pregnancy
- Unable to provide informed consent
- Presence of pulmonary edema
- Heart rate less than 60 beats per minute (bradycardia)
- PR interval longer than 240 milliseconds
- Second- or third-degree atrioventricular (AV) block
- Active asthma
- Known hypersensitivity to metoprolol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tel Aviv Sourasky Medical center
Tel Aviv, Israel
Actively Recruiting
Research Team
S
Shir Frydman, MD
CONTACT
Y
Yishay Szekely, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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