Early Detection of Chronic Thromboembolic Pulmonary Hypertension in Adults After Acute Pulmonary Embolism in the Czech Republic

What this Trial Is About

This research aims to develop, test, and implement a standardized process for early detection of Chronic Thromboembolic Pulmonary Hypertension CTEPH in patients who have had an acute pulmonary embolism APE. It is a national, prospective, multicenter observational pilot project conducted in the Czech Republic. The goal is to improve patient outcomes by enabling timely treatment and to ensure the process is cost-effective and beneficial to the population. Patients who have experienced APE within the past 3 to 12 months and meet specific criteria will undergo a standardized screening protocol to identify early signs of CTEPH. Those found to be at risk will be quickly referred to specialized centers for further evaluation and management. The project plans to involve about 500 patients across approximately 10 selected centers. Participants will be monitored for up to six months from enrollment, during which researchers will assess the accuracy of the screening protocol, the rate of CTEPH detection, and the proportion of patients who follow up at specialized treatment centers. The study includes patient evaluations, data collection on symptoms and risk factors, and referral pathways to ensure rapid access to specialized care. The study is supported by the European Social Fund and the Czech Republics state budget.

Early Detection of CTEPH in Patients After APE