Detecting Familial Hypercholesterolemia Early in Children Aged 2 to 18 in Tarragona Province

What this Trial Is About

Familial Hypercholesterolemia FH is a common genetic condition that causes high levels of low-density lipoproteins LDL-C from birth and increases cardiovascular risk. This research focuses on early detection of Heterozygous FH HeFH in children aged 2 to 18 years, aiming to reduce atherosclerosis progression and cardiovascular problems in adulthood. Early diagnosis also helps identify affected family members, making it a significant public health concern. Children suspected of having FH will be evaluated through genetic testing or clinical criteria, including LDL-C levels and family history. Participants will undergo lifestyle assessments using food frequency questionnaires and physical activity evaluations. The study compares children diagnosed with FH to unaffected children, monitoring lipid levels and healthy habits over up to 10 years to track disease progression. During the study, children and their parents will complete food diaries and provide information on physical activity and tobacco use. Researchers will measure LDL cholesterol levels annually and monitor the number of children diagnosed with FH. The study aims to improve early detection and management of FH in children, supporting better cardiovascular health outcomes later in life.

Early Detection of Familial Hypercholesterolemia in Children