Actively Recruiting

Age: 18Years +
All Genders
NCT06253325

Early Detection of At-risk Septic Patients

Led by University Hospital Southampton NHS Foundation Trust · Updated on 2024-12-02

60

Participants Needed

1

Research Sites

81 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to determine whether additional investigations used in other parts of healthcare can be used in the Emergency Department to identify critically ill patients quicker than usual care.

CONDITIONS

Official Title

Early Detection of At-risk Septic Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Suspected infection as part of the diagnosis
  • Change in quick Sequential Organ Failure Assessment (qSOFA) score of 2 or more or National Early Warning Score 2 (NEWS2) score of 5 or more
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Recent traumatic injury
  • Rockwood frailty score of 6 or higher
  • Previous decisions against critical care therapy being in patient's best interest
  • Critical care therapies started before hospital arrival, including mechanical ventilation, vasopressors/inotropes, sedation or general anesthesia, blood transfusion, or extracorporeal support
  • Advanced directives refusing critical care treatments
  • Acute heart failure
  • Active gastrointestinal bleeding
  • Massive pulmonary embolism
  • Declined ICU admission by critical care team
  • Hospital treatment within 6 hours before Emergency Department arrival

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Southampton NHS Foundation Trust

Southampton, Hampshire, United Kingdom, SO16 6YD

Actively Recruiting

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Research Team

J

James N Ward, BM

CONTACT

A

Ahilanandan Dushianthan, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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