Actively Recruiting
Early Diagnosis and Treatment of Undiagnosed Asthma or COPD: THE UCAP 2 TRIAL
Led by Ottawa Hospital Research Institute · Updated on 2026-01-14
420
Participants Needed
4
Research Sites
280 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Our research group has found that Canadians with undiagnosed asthma or chronic obstructive pulmonary disease (COPD) have increased respiratory symptoms and worse health-related quality of life. The investigators recently developed and validated an on-line questionnaire to accurately identify these symptomatic, undiagnosed individuals. The investigators will advertise in the community asking individuals to complete the on-line questionnaire at home, at their leisure, to determine if they are at risk of asthma or COPD. Those at risk will be invited to participate in a randomized, controlled clinical trial to determine whether early diagnosis of previously undiagnosed asthma or COPD and subsequent treatment by the primary care practitioner will improve their quality of life.
CONDITIONS
Official Title
Early Diagnosis and Treatment of Undiagnosed Asthma or COPD: THE UCAP 2 TRIAL
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals at least 18 years old
- Individuals must have respiratory symptoms
- Individuals must complete the UCAP-Q questionnaire and score a 6% or higher probability of asthma or COPD
- Individuals must give written informed consent to participate
- Individuals must be able to perform pre and post bronchodilator spirometry to measure lung function
- Individuals with undiagnosed airflow obstruction on spirometry (asthma or COPD) will be invited to participate in the randomized controlled trial
You will not qualify if you...
- Individuals previously diagnosed with asthma, COPD, lung cancer, bronchiectasis, interstitial lung disease, cystic fibrosis, or other significant lung diseases
- Individuals currently under the care of a Respirologist
- Individuals currently using inhaled corticosteroids or long-acting bronchodilators
- Individuals with recent history (past 3 months) of myocardial infarction, stroke, aortic or cerebral aneurysm, detached retina, or eye surgery
- Individuals in the third trimester of pregnancy
- Individuals involved in another interventional trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
St. Joseph's Hamilton Healthcare
Hamilton, Ontario, Canada, L8N 4A6
Actively Recruiting
2
Ottawa Hospital General Campus
Ottawa, Ontario, Canada, K1H 8L6
Actively Recruiting
3
Royal University Hospital
Saskatoon, Saskatchewan, Canada
Actively Recruiting
4
Institut universitaire de cardiologie et de pneumologie de Québec
Québec, Canada, G1V 4G5
Actively Recruiting
Research Team
S
Shawn Aaron, MD
CONTACT
K
Kathy Vandemheen, MScN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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