Comparing Early and Late Diet Restart After Colorectal Endoscopic Submucosal Dissection to Improve Recovery and Safety

What this Trial Is About

Researchers are investigating the best timing to restart eating after colorectal endoscopic submucosal dissection ESD, a procedure used to treat certain colorectal lesions. While previous studies on upper gastrointestinal ESD showed that early feeding within one day of the procedure did not increase complications and improved patient satisfaction, no studies have yet examined early feeding after colorectal ESD. This study aims to compare early feeding started within 24 hours after colorectal ESD to delayed feeding started after 24 hours, focusing on adverse events and patient satisfaction. Participants are randomly assigned to one of two groups. In the early feeding group, patients begin drinking water two hours after the procedure if no abnormalities are found during follow-up exams, then progress to a liquid diet and soft diet if no complications arise. In the delayed feeding group, patients fast on the day of the procedure and start a liquid diet 24 hours later, followed by a soft diet if tolerated. Both groups undergo standard colorectal ESD and monitoring such as physical exams, blood tests, and X-rays. Throughout the study, participants provide information on medical history, lesion details, procedure outcomes, and complications. Researchers assess early adverse events within 24 hours and delayed events beyond 24 hours, along with patient satisfaction using surveys. Follow-up visits after discharge help review outcomes and complications. The study collects detailed clinical and laboratory data and uses statistical methods to compare safety and satisfaction between the two dietary timing approaches.

Early Feeding Versus Delayed Feeding After Colorectal Endoscopic Submucosal Dissection