Actively Recruiting
Early Internal Fixation Versus NonOperative Care With Early Rehabilitation for LC1 Fragility Fractures of the Pelvis
Led by University of Southern California · Updated on 2025-10-15
48
Participants Needed
13
Research Sites
163 weeks
Total Duration
On this page
Sponsors
U
University of Southern California
Lead Sponsor
O
Orthopaedic Trauma Association
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this randomized pilot study is to assess feasibility of the trial and to collect information to inform the design of a definitive trial. Adult patients ages 60 years or older with a low-energy lateral compression type 1 (LC1) pelvis fracture with \<10 mm initial displacement of the posterior pelvic ring will be eligible to participate in the study. Patients will be randomized to one of two treatment groups, early internal fixation or nonoperative care with early rehabilitation, defined as at least five days of attempted mobilization by rehabilitation providers. Participants will be followed for 1 year.
CONDITIONS
Official Title
Early Internal Fixation Versus NonOperative Care With Early Rehabilitation for LC1 Fragility Fractures of the Pelvis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient 60 years of age or older
- Low energy injury from a fall from standing height
- Confirmed LC1 pelvis fracture by X-ray, CT, or MRI
- Fracture suitable for either early internal fixation or nonoperative care with rehabilitation
- Fracture displacement less than 10 mm on CT scan
- Injury occurred within 21 days before screening
You will not qualify if you...
- Patient unable to walk before injury
- Other injury or condition preventing weightbearing after surgery
- Retained pelvic implants limiting treatment options
- Infection near the hip (soft tissue or bone)
- Pathologic fracture with bone lesion preventing fixation
- Too ill for internal fixation or nonoperative care as judged by surgeon
- Difficulty maintaining follow-up
- Expected survival less than 12 months due to illness or injury
- Currently enrolled in a conflicting study
- Prior enrollment in this trial
- Unable to consent due to language or lack of authorized representative
- Declined participation or not approached
- Other exclusion reasons approved by the study Methods Centre
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 13 locations
1
University of Arizona
Phoenix, Arizona, United States, 85006
Not Yet Recruiting
2
Keck Medical Center of USC
Los Angeles, California, United States, 90033
Actively Recruiting
3
Los Angeles General Medical Center
Los Angeles, California, United States, 90033
Actively Recruiting
4
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
Actively Recruiting
5
University of California, Davis
Sacramento, California, United States, 95817
Actively Recruiting
6
University of California San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
7
Indiana University
Indianapolis, Indiana, United States, 46202
Actively Recruiting
8
University of Maryland, Baltimore - R Adams Cowley Shock Trauma Center
Baltimore, Maryland, United States, 21201
Actively Recruiting
9
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Not Yet Recruiting
10
The Curators of the University of Missouri - Missouri Orthopaedic Institute
Columbia, Missouri, United States, 65201
Actively Recruiting
11
University of Utah
Salt Lake City, Utah, United States, 84112
Actively Recruiting
12
University of Washington - Harborview Medical Center
Seattle, Washington, United States, 98104
Actively Recruiting
13
Research Institute Vall d'Hebrón - Vall d'Hebron University Hospital
Barcelona, Spain, Spain, 08035
Not Yet Recruiting
Research Team
P
Pui Yan, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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