Actively Recruiting
Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation
Led by Beijing Anzhen Hospital · Updated on 2026-03-24
358
Participants Needed
1
Research Sites
140 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this multicenter, randomized trial is to compare early early left ventricular unloading by Intra-aortic Balloon Pump (IABP) versus conventional approach in patients with cardiogenic shock (CS) undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO). The main question it aims to answer is : • If left ventricular unloading by IABP as compared with the conventional approach will improve the outcomes in patients undergoing VA-ECMO.
CONDITIONS
Official Title
Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age of 18 years or older
- Diagnosis of cardiogenic shock defined by systolic blood pressure less than 90 mm Hg for more than 30 minutes or use of catecholamines to maintain systolic pressure above 90 mm Hg
- Arterial lactate level greater than 3 mmol per liter
- Signs of impaired organ perfusion
- Successful implantation of peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO)
- Provision of informed consent
You will not qualify if you...
- SCAI shock stage A or B
- Moderate to severe aortic insufficiency or aortic dissection
- Severe peripheral vascular disease
- Post-cardiotomy cardiogenic shock excluding coronary artery bypass grafting procedures
- Use of VA-ECMO for definite non-cardiac causes
- Isolated right ventricular failure
- VA-ECMO use limited to surgical or other intervention periods
- Ischemic mechanical complications such as ventricular septal defect or papillary muscle rupture
- Extracorporeal cardiopulmonary resuscitation
- Presence of LVAD, Impella, or IABP devices in place
- Severe bleeding
- Terminal malignancy
- Irreversible neurologic injury
- Pregnancy or lactation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Beijing Anzhen Hospital
Beijing, Beijing Municipality, China, 100029
Actively Recruiting
Research Team
X
Xiaotong Hou, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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