Comparing Early and Late Tracheostomy in Adults with Guillain-Barre Syndrome on Mechanical Ventilation to Improve Recovery and Hospital Stay

What this Trial Is About

This research aims to investigate the timing of tracheostomy in patients with Guillain-Barre syndrome who require prolonged mechanical ventilation. The study compares early tracheostomy, performed less than 7 days from intubation, with late tracheostomy, performed more than 7 days after intubation. The goal is to evaluate whether early tracheostomy is linked to fewer ventilation days, lower mortality, and shorter stays in the hospital and ICU. The study groups include patients who received early tracheostomy and those who had late tracheostomy during their intensive care unit stay. This is an observational study reviewing clinical outcomes retrospectively. Both groups consist of mechanically ventilated patients diagnosed with Guillain-Barre syndrome admitted to the ICU. Participants are involved through data collection from their ICU stay records between 2012 and 2024. Researchers will assess ventilation duration over one year from intubation as the primary outcome. Additional outcomes include mortality and length of hospital and ICU stay. The study is sponsored by Meir Medical Center and participants clinical progress is monitored through existing medical records.

Early vs. Late Tracheostomy in Patients With Guillain -Barre Syndrome