Actively Recruiting

Age: 18Years +
All Genders
NCT07276425

Early and Long-Term Efficacy and Immune Changes With Dupilumab in Prurigo Nodularis

Led by UMC Utrecht · Updated on 2025-12-18

40

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

Sponsors

U

UMC Utrecht

Lead Sponsor

S

Sanofi

Collaborating Sponsor

AI-Summary

What this Trial Is About

With the arrival of dupilumab as the first available targeted therapy for PN, there is an unmet need for real-world data and translational research on the working mechanism of dupilumab on PN, to optimize individualized targeted treatment.

CONDITIONS

Official Title

Early and Long-Term Efficacy and Immune Changes With Dupilumab in Prurigo Nodularis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients with moderate-to-severe prurigo nodularis starting dupilumab treatment
Not Eligible

You will not qualify if you...

  • Unwilling to participate in the BioDay registry
  • Unwilling to participate in UMC Utrecht Biobank (for translational endpoints only)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Medical Center Utrecht

Utrecht, Utrecht, Netherlands

Actively Recruiting

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Research Team

M

Marjolein de Bruin-Weller, Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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