Actively Recruiting

Age: 18Years - 40Years
All Genders
NCT06965335

Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study

Led by Niguarda Hospital · Updated on 2025-05-11

20

Participants Needed

1

Research Sites

167 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Observational, retrospective and prospective multicentric Italian study of patients diagnosed with colorectal cancer between age 18-40, aiming at underpinning the biology of vEO-CRC, including colibactin as well as a broader proteo-genomic characterization, to identify potential new therapeutic targets specifically directed to this peculiar subset of patients.

CONDITIONS

Official Title

Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study

Who Can Participate

Age: 18Years - 40Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with colorectal cancer between 18 and 40 years old (vEO-CRC) or diagnosed at age 60 or older (SO-CRC)
  • Signed informed consent if the patient is alive
  • Availability of tumor tissue samples including formalin-fixed paraffin embedded (FFPE) slides or fresh tumor tissue from biopsy or surgery
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

ASST Grande Ospedale Metropolitano Niguarda

Milan, Milano, Italy, 20162

Actively Recruiting

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Research Team

S

Salvatore Siena, MD

CONTACT

A

Andrea Sartore Bianchi, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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