Actively Recruiting
Early PKD Observational Cohort Study
Led by University of Kansas Medical Center · Updated on 2026-04-27
250
Participants Needed
3
Research Sites
791 weeks
Total Duration
On this page
Sponsors
U
University of Kansas Medical Center
Lead Sponsor
N
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.
CONDITIONS
Official Title
Early PKD Observational Cohort Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with early stage autosomal dominant polycystic kidney disease (ADPKD) with family history of PKD
- Glomerular filtration rate (GFR) greater than 80 ml/min per 1.73 m2
- Includes all races and ethnic groups
- Healthy volunteers with no family history of kidney disease
- Normal GFR in healthy volunteers
- Male or female participants
- Age between 4 and 35 years
You will not qualify if you...
- Diabetes mellitus (both insulin-dependent and non-insulin dependent)
- Systemic illnesses such as systemic lupus erythematosus or vasculitis
- Unable to provide written informed consent
- Unavailable for magnetic resonance imaging (MRI) and blood/urine sample collection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
University of Chicago
Chicago, Illinois, United States, 60637
Actively Recruiting
2
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160
Actively Recruiting
3
Children's Mercy Hospital
Kansas City, Missouri, United States, 64108
Actively Recruiting
Research Team
C
Cathy Creed, RN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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