Actively Recruiting

Age: 18Years - 80Years
FEMALE
NCT06282796

Early Prediction and Warning for Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy

Led by First Hospital of China Medical University · Updated on 2024-02-28

600

Participants Needed

5

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This multicenter clinical study aims to build an intelligent and accurate diagnosis and dynamic prediction and early warning model of cardiotoxicity due to anthracycline-based breast cancer chemotherapy, clarify the value of the early warning model in guiding the targeted prevention of myocardial protection, providing an important theoretical basis for reducing the mortality rate of breast cancer and improving the prognosis.

CONDITIONS

Official Title

Early Prediction and Warning for Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy

Who Can Participate

Age: 18Years - 80Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Histologically or cytopathological confirmed stage I-III HER2-positive breast cancer
  • Scheduled to receive consecutive anthracycline chemotherapy or sequential trastuzumab targeted therapy
  • Left ventricular ejection fraction 53% or higher before chemotherapy
Not Eligible

You will not qualify if you...

  • Life expectancy 12 months or less
  • Participation in other ongoing oncology clinical trials
  • Prior treatment with anthracyclines or chest radiation therapy
  • Pregnant or lactating women
  • Very poor quality ultrasound images of the heart

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Fujian Cancer Hospital

Fuzhou, Fujian, China

Actively Recruiting

2

Dalian Friendship Hospital

Dalian, Liaoning, China

Actively Recruiting

3

Dalian Municipal Central Hospital

Dalian, Liaoning, China

Actively Recruiting

4

Liaoning Cancer Hospital & Institute

Shenyang, Liaoning, China

Actively Recruiting

5

The Third People's Hospital Of Chengdu

Chengdu, Sichuan, China

Actively Recruiting

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Research Team

Y

Yonghuai Wang, Ph.D

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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